One of the early chapters that was poignant in my opinion was Chapter 4: What Are the Instruments of Good Works. This chapter is a thorough list of ways to behave in accordance with the will of God. It immediately reminded me of my class on the Buddha, because the Buddhists are obsessed with lists. The Buddha's lists are definitely more concise; many of Benedict's bullet points same nearly identical things.
Even conceding the redundancies, and approaching the text without a real religious backdrop, many of these decrees are still worthy endeavors. For example: "not to become attached to pleasures," "to keep constant guard over the actions of one's life," and "then not to murder" are all pretty decent tid-bits of advice. Some, though, are a little more heavy handed, like "to love fasting" and to attribute to God, and not to self, whatever good one sees in oneself... but to recognize that always that the evil is one's own doing, and to impute it to oneself."
I do believe it is important to bear responsibility for one's own shortcomings in life, considering we all have a handful, but I do not think that it is healthy to internalize everything bad you do and externalize everything good.